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Crystalline Oral Anabolic Steroids Anastrozole Anti Breast Cancer CAS 120511-73

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Crystalline Oral Anabolic Steroids Anastrozole Anti Breast Cancer CAS 120511-73

Brand Name : Hongkong SaiChuang
Model Number : 120511-73-1
Certification : ISO9001
Place of Origin : China
MOQ : 10g
Price : negotiable USD
Payment Terms : D/P, L/C, D/A, D/P, T/T, Western Union
Supply Ability : 10000KG/Month
Packaging Details : as requested
Name : Anastrozole
CAS : 120511-73-1
MF : C17H19N5
MW : 293.37
Purity : 99%
Origin : China
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Anastrozole Anti Breast Cancer oluble in acetonitrile Inhibit intoestrone Crystalline Solid 120511-73-1


Product Description

Chemical Name: ANASTROZOLE
CAS No.: 120511-73-1
Molecular Formula: C17H19N5
Molecular Weight: 293.37
mp 81-82°C
storage temp. Store at RT
Chemical Properties: Crystalline Solid
Package: 25KG/Drum
Standard: Enterprise Standard
Usage: It can be used to the treatment of Breast cancer
Synonyms: ICI-D-1033;ARIMIDEX;1-[3,5-DI-(1-METHYL-1-CYANO)-ETHYL]-BENZYL-1,2,4-TRIAZOLE;ANASTRAZOLE;ANASTROZOLE;tetramethyl-5-(1h-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile;ZD-1033;1,3-benzenediacetonitrile,alpha,alpha,alpha’,alpha’-tetramethyl-5-(1h-1,2,4-t


Description

The drug is appropriately used when using substantial amounts of aromatizing , or when one is prone to gynecomastia . Arimidex does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso than Cytadren. It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.



Applications

  • Anastrozole (INN) is a non-steroidal aromatase-inhibiting drug approved for treatment of breast cancer after surgery. Pharmaceutical raw materials , Oncology drug ,anti breast cancer
  • Anastrozole is used for Postmenopausal women with advanced breast cancer that tamoxifen and other anti-estrogen therapy can not control. For the estrogen receptor-negative patients, can think about the anastrozole if the tamoxifen showed positive clinical response.
  • Anastrazole is used to treat postmenopausal women with estrogen receptor positive breast cancer. This drug is often given in conjunction with other drugs such as tamoxifen in early stage cancers. Anastrazole is taken in tablet form usually just once a day.


    Side Effects: Common side effects include hot flashes, nausea, decreased energy, back and bone pain, joint pain or stiffness. Side effects may differ from those listed above if anastrazole is being taken with other medications.


    Medicinal categories: non-steroidal aromatase inhibitors

    Indication: Anastrozole is used for Postmenopausal women with advanced breast cancer that tamoxifen and other anti-estrogen therapy can not control. For the estrogen receptor-negative patients, can think about the anastrozole if the tamoxifen showed positive clinical response.

    Pharmacology: Anastrozole as a potent, selective nonsteroidal aromatase inhibitors, it can inhibit the postmenopausal patients with adrenal suppression generated intoestrone, significantly reduce plasma estrogen levels. And inhibiting of breast tumor growth. Anastrozole significantly affect on adrenal corticosteroids or aldosterone.


Specifications

ItemsStandardResults
DescriptionWhite crystalline powderComplies
Identification

IR

HPLC

Reactive

Conform with standard IR

Conform with standard HPLC

Conform

SolubilityFreely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrileComplies
Total Impuritymax.0.5%0.18%
Total Unspecified Impuritymax. 0.2%0.08%
Individual unspecified impurltymax. 0.1%0.05%
Related compound Bmax. 0.2%0.07%
Related compound Cmax. 0.2%0.04%
Related compound Dmax. 0.1%0.05%
Related compound Emax. 0.1%0.06%
Limit of cyclohexanemax. 0.08%ND
Limit of ethylacetatemax. 0.1%0.07%
Melting point81.0~84.0°C82.5~83.2°C
Watermax. 0.3%0.21%
Residue on ignitionmax. 0.1%0.07%
Heavy Metalsmax.0.001%Complies
Assay(HPLC)98.0%~102.0%99.8%
StorageCool and dry

COA:

ItemsStandardResults
DescriptionOff White crystalline powderComplies
SolubilityFreely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrileComplies
Total Impuritymax.0.5%0.18%
Total Unspecified Impuritymax. 0.2%0.08%
Individual unspecified impurltymax. 0.1%0.05%
Related compound Bmax. 0.2%0.07%
Related compound Cmax. 0.2%0.04%
Related compound Dmax. 0.1%0.05%
Related compound Emax. 0.1%0.06%
Limit of cyclohexanemax. 0.08%ND
Limit of ethylacetatemax. 0.1%0.07%
Melting point81.0~84.0°C82.5~83.2°C
Watermax. 0.3%0.21%
Residue on ignitionmax. 0.1%0.07%
Heavy Metalsmax.0.001%Complies
Assay(HPLC)98.0%~102.0%99.8%
StorageCool and dry
ConclusionIt complies to USP32 .
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can make payment accordingly.
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A:You can get free samples for some products,you only need to pay the shipping
cost or arrange a courier to us and take the samples. You can send us your
product specifications and requests,we will manufacture the products according
to your requests.
Q: What’s your MOQ
A:For the high value product, our MOQ starts from 1g and generally starts
from 1kgs. For other low price product, our MOQ starts from 10kg and 100kg.
Q: Is there a discount
A: Yes, for larger quantity, we alway support with better price.
Q:How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero.
If there is a quality problem caused by us, we will send you free goods for
replacement or refund your loss.
Q:How to contact us
A:You can choose your interested products and send inquiry to us.You can
dial our telephone directly, you will get our reply.
Our Superiority

Quality

our products meet msds safe standard and we have iso and other certificate so yan can get high quality products from our company.


Packing

we can do according to the customers' request.


Delivery

We can pack your powders within 12 hours after your payment, and corresponding picture of your powders' parcel will be sent to you.

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