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Ambrisentan treatment of pulmonary hypertension hypertension Pharmaceutical

Hongkong  Saichuang  Pharmaceutical  Technology  Co.,Ltd
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Ambrisentan treatment of pulmonary hypertension hypertension Pharmaceutical

Brand Name : Hongkong SaiChuang
Model Number : 616204-22-9
Certification : ISO9001
Place of Origin : China
MOQ : 10g
Price : negotiable USD
Payment Terms : Western Union, L/C, , D/A, MoneyGram, T/T, D/P
Supply Ability : 1000KG/month
Delivery Time : within 12 hours after payment
Packaging Details : safe discreet package
Origin : ZheJiang
Name : Ambrisentan
WhatsApp : +86 18873303856
Email : majorina.cai@chembj.com
CAS : 177036-94-1
Tel : +86 18873303856
MF : C22H22N2O4
MW : 378.42
Purity : 99%
Appearance : White crystalline powder
Packaging : discreet packaging
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Ambrisentan treatment of pulmonary hypertension hypertension Pharmaceutical Grade Ambrisentan CAS:177036-94-1


Basic INFORMATION


Name:Ambrisentan

Molecular Formula: C22H22N2O4

Molecular Weight: 378.42

CAS No.: 177036-94-1

Assay: 99%

Application : Ambrisentan is a nonpeptide endothelin ETA receptor antagonist and antihypertensive.

Appearance:Almost white to white crystalline powder

Storage: Stored in cool & dry place; Kept away from strong light and heat


What is Ambrisentan​ ​?


Ambrisentan is a drug used to treat pulmonary hypertension. Peptide endothelin contracts muscles in blood vessels and increases blood pressure. Amphetamine, which relaxes these muscles, is an endothelin receptor antagonist and is selective for type A endothelin receptors. In two double-blind, multicenter trials, Ambrisentan significantly improved exercise capacity compared with placebo.

Used for?
Ambrisentan is used to treat high blood pressure in the lungs (pulmonary arterial hypertension). This condition is thought to be caused by increased levels of a certain natural substance (endothelin-1). This medication blocks the effects of endothelin-1, thereby helping to decrease the blood pressure in the lungs, slow the worsening of symptoms, and improve your ability to exercise.
COA
ItemSpecificationsResults
CharacterWhite or white crystalline powderWhite powder
IdentifyHPLC/UVConforms
Isomeride≤0.5%0.023%
Related substanceSingle impurity shall not be over 0.1% Single impurity shall not be over 0.1%Single impurity 0.02%0.031% of the total noise
Water≤0.5%0.01%
Residue on ignition≤0.1%0.03%
Heavy metalMay not have twenty over one million<10ppm
Assaying98.0%~102.0%99.18%
ConclusionThe results conforms with enterprise standards

Function

Ambrisentan is a drug indicated for use in the treatment of pulmonary hypertension. It functions as an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA).


Application of Ambrisentan :


Clinical use

The ambriententa is classified as a WHO class for the treatment of pulmonary arterial hypertension (WHO Group 1) for improvement of morbidity and delayed clinical signs of II or III symptoms.

Safety and side effects

Stuffy nose, runny nose, or flushing may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Tell your doctor right away if you have any serious side effects, including: fast heartbeat, extreme tiredness, swelling ankles/feet, sudden/unexplained weight gain.

Other medications that are like ambrisentan may rarely cause very serious liver problems. Tell your doctor right away if you develop symptoms of liver disease, including: persistent nausea/vomiting, loss of appetite, severe stomach/abdominal pain, dark urine, yellowing eyes/skin.

This medication can decrease sperm production in some men, an effect that may lower male fertility. Consult your doctor for more details.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.


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FAQ

How to start orders or make payments

A:You can send our your Purchase order(if your company has), or just
send a simple confirmation by email or by Trade Manager, and we will send
you Proforma Invoice with our bank details for your confirmation, then you
can make payment accordingly.
Q: How to confirm the Product Quality before placing orders
A:You can get free samples for some products,you only need to pay the shipping
cost or arrange a courier to us and take the samples. You can send us your
product specifications and requests,we will manufacture the products according
to your requests.
Q: What’s your MOQ
A:For the high value product, our MOQ starts from 1g and generally starts
from 1kgs. For other low price product, our MOQ starts from 10kg and 100kg.
Q: Is there a discount
A: Yes, for larger quantity, we alway support with better price.
Q:How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero.
If there is a quality problem caused by us, we will send you free goods for
replacement or refund your loss.
Q:How to contact us
A:You can choose your interested products and send inquiry to us.You can
dial our telephone directly, you will get our reply.
Our Superiority
Price
Best prices you're sure to be satisfied, the more you buy, the more competitive prices you get.
Packing
Professional packing with professional materials, and We'll give clients several Packing way to choose after you contact me through my email
Quality
Our company is a professional leading factory in China in pharmaceutical area, ach batch of steroid powders have to tested by our QC(quality control) department before they are allowed to sell.
Payment
T/T in advance, WU,Money Gram and Bitcoin
Delivery
We can pack your powders within 12 hours after your payment, and corresponding picture of your powders' parcel will be sent to you.
We are one of the leading manufacturers and exporters in China. We specialize in anabolic steroids, peptides,SARMs,fat burner and pharmaceutical intermediates. If you have any questions of our products that you are interested in, please contact as without hesitate.

Payment & Shipping Terms:

Minimum Order Quantity: 10g

Price: Negotiated

Packaging Details: Dicreet package

Delivery Time: Within 12 hours after confirming the payment

Payment Terms: T/T, Western Union, MoneyGram, Bitcoin

Supply Ability: 1000kg/Month

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